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The National Health and Nutrition Examination Survey data suggest that chronic diarrhoea is almost twice as common in people with type 1 and type 2 diabetes compared with nondiabetic controls (about 11% vs 6%)

83 Although animal research suggests hops do not strongly trigger proliferation in endometrial and breast tissues, there have been reports of endometrial thickening and bleeding in postmenopausal women using hops, and its long-term safety in women with a history or high risk of breast cancer is uncertain

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Timing the medication earlier in the day often prevents sleep disturbances